Stay in the know.

Join our free nurse community to get updates on trending questions and the topics you care about

What are the typical medications you give in the PACU?


October 2nd, 2021

There are many: For pain usually Fentanyl, sometimes Dilaudid, IV Tylenol. For nausea, Zofran or Phenergan and sometimes compazine, although not often because it can be a bit sedating and hangs on for a while after administration. Antibiotics will vary depending on type of surgery and surgeon preference based on area of entry/what they encountered during the case. IV fluids are usually standard I’ve found-NSS or Lactated ringers in specific.

The bigger thing to remember is that these are just general medications you may see. Each institution and surgical service will decide what medications they want their patients to receive directly post-op, but knowing your pain medications and anti-emetics and antibiotics are a good start!

September 29th, 2021

Usually we give Toradol, IV Acetaminophen, Zofran and occasionally some PO Oxycodone for pain relief.

October 2nd, 2021

Narcotic analgesics (IV first, PO when able) and anti-emetics are the usual medications given in PACU. In recent years there has been movement toward non-narcotic pain relievers to reduce narcotic use. The medications preferred varies from region to region.

October 1st, 2021

Every IV pain medication under the sun, labetalol, hydralazine, Demoral, zofran, and phenergan. Those are the typical drugs in my experience.

January 16th, 2024

1. Fentanyl 25-50 mcg IV
2. Hydromorphine 0.25-0.5 mg IV
3. Morphine 2-4 mg IV. (I only use this if I need a multimodal pain management approach and their BP systolic is also above 110 (it causes vasodilation and can drop their BP. It’s not all that great on its own but as a multimodal approach it helps to potentials the others.)
4. IV acetaminophen: our anesthesia providers often give this in the OR, but if not, GREAT addition to multimodal pain management.
5. Toradol (ketorolac) 15-30mg IV. EFFECTIVE. Great addition to multimodal armamentarium !
6. Oxycodone 5mg po. I like to send them home or to floor with this on board. Gets them home more comfortably or through the admission process on the unit.
7. Ondansetron first line for nausea, but if they already got 8 mg in OR, move on to the 2nd drug.
8. Compazine - great drug for n/v. Also has some sedative effects.
9. Phenergan supp- if indicated. Many gastric sleeves have gotten this in the OR already.
10. BP meds:
Hydralazine IV
Labetalol IV

Don’t underestimate the power of a fluid “bolus” for n/v. Often the pt is dehydrated and this will reduce n/v. (A simple alcohol wipe placed on the O2 tubing near their nose helps nausea too!!)

December 10th, 2023

Fentayl , hydromorphone , versed Demerol iv Tylenol , Oxcodone zofran and phenergan

June 13th, 2022

Fentanyl, dilaudid, zofran, phenergan, oxycodone, IV Tylenol

May 28th, 2022

pain meds, IV or oral (mainly IV), oxygen, antiemetic (zoltan, phenergen), antibiotics, IV fluids and if the patient is awaiting a bed in the PACU for a while, we restart their home meds like BP meds, siezure meds etc..

October 2nd, 2021

I don’t work in the PACU